Trust architecture & clinical proof

Show the work. Never assert it.

Every active in every NeoSelf formula is dosed at the concentration used in the study behind it — published in full, on the back of the object. No proprietary blends. No "active complex." Just the number.


The proof ladder

Every claim runs it.

If we can't show the mechanism, the dose, the study, the independent check and the published data — we don't say it.

01

Mechanism

What the active does at a cellular level, in plain language.

02

Dose

The exact concentration used — matched to the studied range.

03

Study

The clinical literature this formulation is built against.

04

3rd-party

Independent lab verification — not self-reported.

05

Published

Full INCI, full percentages, on every pack. Always.


Mechanism, translated

The lab, for the counter.

How the hero actives across the system actually work.

TX-ACID · 5.0% · PIGMENTATION

Tranexamic acid interrupts the signalling pathway between skin cells and pigment-producing cells — reducing the trigger for excess melanin production at its source, in Repair™.

NIACINAMIDE · 3–4% · BARRIER + TONE

Vitamin B3 at studied concentrations regulates oil production, reduces the transfer of pigment to surface skin cells, and reinforces the skin's barrier — present across Defend™ and Repair™.

ENCAPSULATED RETINALDEHYDE · 0.05%

Retinaldehyde converts to active retinoid form in skin with one fewer conversion step than retinol. Encapsulation releases it gradually overnight, in Repair™ — supporting renewal while minimising the irritation typical of free retinoids.

PHENYLETHYL RESORCINOL · 0.2%

A direct tyrosinase inhibitor — it blocks the enzyme responsible for melanin synthesis, dosed conservatively in Defend™ for daily-wear tolerance.

ECTOIN · 1.0% · EXTREMOLYTE

Originally identified in organisms that survive extreme heat and dryness, Ectoin stabilises cell membranes against environmental stress — UV, heat and pollution — in Defend™ and Repair™.

SALICYLIC ACID · 0.5% · CLEAN™

A beta-hydroxy acid that penetrates into the pore lining to clear oil and debris — dosed low enough for daily use without compromising the barrier.


Certifications — the floor

Not a claim. A checklist.

✓ ISO 22716 / GMP Manufacture
✓ Dermatologically & Allergy-Tested
✓ Third-Party Clinically Trialled
✓ Leaping Bunny · Cruelty-Free & Vegan
✓ Fragrance-Free · Paraben-Free
✓ Heavy-Metal & Microbiologically Tested